{"id":11,"date":"2024-05-06T12:09:36","date_gmt":"2024-05-06T15:09:36","guid":{"rendered":"https:\/\/projects.upei.ca\/seiblab\/?page_id=11"},"modified":"2026-07-14T13:00:54","modified_gmt":"2026-07-14T16:00:54","slug":"publications","status":"publish","type":"page","link":"https:\/\/projects.upei.ca\/seiblab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

2026<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>*, Liu MQ*, Tobiansky DJ, Floresco SB&<\/sup>, Soma KK&<\/sup>. A Novel Operant Conditioning Task to Assess Motivation to Exercise in Rats. *, co-author,\u00a0&<\/sup>\u00a0co-PI. BioRXiv 2026 July https:\/\/doi.org\/10.64898\/2026.07.07.7370<\/a><\/p>\n\n\n\n

Ward MD, Snyder JS, Seib DR<\/strong>. Chemogenetic inhibition of developmentally-born hippocampal neurons but not loss of adult neurogenesis impairs spatial working memory in the rat. Behavioural Brain Research<\/strong> 2026 May 28:506:116151. https:\/\/doi.org\/10.1016\/j.bbr.2026.116151<\/a> PMID: 41806956<\/p>\n\n\n\n

Jung MM, Idrissi M, Hoang Y, Huan T, Seib DR<\/strong>, Soma K. Maternal sucrose intake during pregnancy alone disrupts testosterone and allopregnanolone levels in the fetal brain of rats<\/a>. The Journal of Nutrition<\/strong> 2026 Feb;156(2):101267. https:\/\/doi.org\/10.1016\/j.tjnut.2025.101267<\/a> PMID: 41386554<\/p>\n\n\n\n

2025<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Jung MM, Soma KK. Maternal sucrose consumption alters steroid levels in the mother, placenta and fetus<\/a>. Journal of Endocrinology<\/strong> 2025 Feb 24;265(1):e240238. https:\/\/doi.org\/10.1530\/JOE-24-0238<\/a> PMID: 39873388<\/p>\n\n\n\n

2023<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Tobiansky DJ, Meitzen J, Floresco SB, Soma KK. Neurosteroids and the mesocorticolimbic system<\/a>. Neuroscience and Biobehavioral Reviews <\/strong>2023 153, 105356. https:\/\/doi.org\/10.1016\/j.neubiorev.2023.105356<\/a>. PMID: 37567491<\/p>\n\n\n\n

Price HR, Jalabert C, Seib DR<\/strong>, Ma C, Lai D, Soma KK, Collier AC. Measurement of Steroids in the Placenta, Maternal Serum, and Fetal Serum in Humans, Rats, and Mice: A Technical Note<\/a>. Separations<\/strong> 2023 10<\/em>(4), 221; https:\/\/doi.org\/10.3390\/separations10040221<\/a>. <\/p>\n\n\n\n

Ash AM, Regele-Blasco E, Seib DR<\/strong>, Chahley E, Skelton PD, Luikart BW, Snyder JS. Adult-born neurons inhibit developmentally-born neurons during spatial learning<\/a>. Neurobiol. Learn. Mem.<\/strong> 2023, 198, 107710. doi.org\/10.1016\/j.nlm.2022.107710<\/a>. PMID: 36572174<\/p>\n\n\n\n

2022<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Princz-Lebel O, Chahley ER, Floresco SB, Snyder JS. Hippocampal neurogenesis promotes effortful responding but does not regulate effort-based choice<\/a>. Hippocampus<\/strong> 2022 Sep 30.  doi.org\/10.1002\/hipo.23472<\/a>. PMID: 36177887<\/p>\n\n\n\n

O’Leary TP, Askari B, Lee B, Darby K, Knudson C, Ash AM, Seib DR<\/strong>, Espinueva D, Snyder JS. Inhibiting adult neurogenesis differentially affects spatial learning in females and males<\/a>. eNeuro<\/strong> 2022 May 12;9(3): ENEURO.0054-22.2022. doi.org\/10.1523\/ENEURO.0054-22.2022<\/a>. PMID: 35473765<\/p>\n\n\n\n

Tomm RJ*, Seib DR*<\/strong>, Kachkovski GV, Schweitzer HR, Tobiansky DJ, Floresco SB&<\/sup>, Soma KK&<\/sup>. Androgen synthesis inhibition increaes behavioural flexibility and tyrosine hydroxylase in gonadectomized male rats<\/a>. *, equal contribution, &<\/sup> co-PI. J Neuroendocrinol <\/strong>2022 Jun;34(6):e13128. doi.org\/10.1111\/jne.13128<\/a>. PMID: 35583989<\/p>\n\n\n\n

2021<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Espinueva DF, Princz-Lebel O, Chahley E, Stevenson J, O’Leary TP, Floresco SB, Snyder JS. Hippocampal neurogenesis promotes preference for future rewards<\/a>.<\/a> Mol Psychiatry<\/strong>. 2021 Nov;26(11):6317-6335. doi: 10.1038\/s41380-021-01165-3. PMID: 34021262<\/p>\n\n\n\n

Comment by Thuret S: Faculty Opinions Recommendation<\/a><\/strong> of [Seib DR et al., Mol Psychiatry 2021]. In Faculty Opinions, 16 Jun 2021; 10.3410\/f.740158880.793585885<\/em><\/p>\n\n\n\n

2020<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Espinueva DF, Floresco SB, Snyder JS. A role for neurogenesis in probabilistic reward learning.<\/a> Behav Neurosci<\/strong>. 2020 Aug;134(4):283-295. doi.org\/10.1037\/bne0000370<\/a>. Epub 2020 May 7. PMID: 32378907<\/p>\n\n\n\n

Cole JD, Espinueva DF, Seib DR<\/strong>, Ash AM, Cooke MB, Cahill SP, O’Leary TP, Kwan SS, Snyder JS. Adult-Born Hippocampal Neurons Undergo Extended Development and Are Morphologically Distinct from Neonatally-Born Neurons.<\/a> J Neurosci<\/strong>. 2020 Jul 22;40(30):5740-5756. doi.org\/10.1523\/JNEUROSCI.1665-19.2020<\/a>. Epub 2020 Jun 22. PMID: 32571837<\/p>\n\n\n\n

Covered in Nature Research Highlights<\/strong><\/a>: Neurons that bloom in adulthood show off fancy patterns. 22 Jun 2020.<\/em><\/p>\n\n\n\n

2019<\/strong><\/p>\n\n\n\n

Yu RQ, Cooke M, Seib DR<\/strong>, Zhao J, Snyder JS. Adult neurogenesis promotes efficient, nonspecific search strategies in a spatial alternation water maze task.<\/a> Behav Brain Res<\/strong>. 2019 Dec 30;376:112151. doi.org\/10.1016\/j.bbr.2019.112151<\/a>. Epub 2019 Aug 22. PMID: 31445978<\/p>\n\n\n\n

Cahill SP, Martinovic A, Cole JD, Seib DR<\/strong>, Snyder JS. A combination of running and memantine increases neurogenesis and reduces activation of developmentally-born dentate granule neurons in rats.<\/a> Behav Brain Res<\/strong>. 2019 Oct 17;372:112005. doi.org\/10.1016\/j.bbr.2019.112005<\/a>. Epub 2019 Jun 2. PMID: 31167109<\/p>\n\n\n\n

2018<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Chahley E, Princz-Lebel O, Snyder JS. Intact memory for local and distal cues in male and female rats that lack adult neurogenesis.<\/a> PLoS One<\/strong>. 2018;13(5):e0197869. doi.org\/10.1371\/journal.pone.0197869<\/a>. eCollection 2018. PMID: 29787617<\/p>\n\n\n\n

2016<\/strong><\/p>\n\n\n\n

Snyder JS, Grigereit L, Russo A, Seib DR<\/strong>, Brewer M, Pickel J, Cameron HA. A Transgenic Rat for Specifically Inhibiting Adult Neurogenesis.<\/a> eNeuro<\/strong>. 2016 May-Jun;3(3). doi.org\/10.1523\/ENEURO.0064-16.2016<\/a>. eCollection 2016 May-Jun. PMID: 27257630<\/p>\n\n\n\n

2015<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Martin-Villalba A. Neurogenesis in the Normal Ageing Hippocampus: A Mini-Review.<\/a> Gerontology<\/strong>. 2015;61(4):327-35. doi.org\/10.1159\/000368575<\/a>. Epub 2014 Nov 29. Review. PMID: 25471300<\/p>\n\n\n\n

2013<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Corsini NS, Ellwanger K, Plaas C, Mateos A, Pitzer C, Niehrs C, Celikel T, Martin-Villalba A. Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline.<\/a> Cell Stem Cell<\/strong>. 2013 Feb 7;12(2):204-14. doi.org\/10.1016\/j.stem.2012.11.010<\/a>. PMID: 23395445.<\/p>\n\n\n\n

Comment by Wu MV and Hen R. The young and the restless: regulation of adult neurogenesis by Wnt signaling. Cell Stem Cell<\/a><\/strong>. 2013 Feb 7;12(2):139-40. doi.org\/10.1016\/j.stem.2013.01.013<\/a>.<\/em> PMID: 23395437<\/p>\n\n\n\n

Covered in National Geographic<\/a> <\/strong>by Virginia Hughes: Opening the Black Box of Neurogenesis. 7 Feb 2013.<\/em><\/p>\n\n\n\n

Seib DR<\/strong> and Martin-Villalba A (2013). In vivo<\/em><\/a> Neurogenesis<\/a>. Bio-protocol <\/strong>3(15): e841. http:\/\/doi.org\/10.21769\/BioProtoc.841<\/a>.<\/p>\n\n\n\n

Seib DR<\/strong> and Martin-Villalba A (2013). Neuronal Morphology Analysis<\/a>. Bio-protocol<\/strong> 3(15): e842. http:\/\/doi.org\/10.21769\/BioProtoc.842<\/a>.<\/p>\n\n\n\n

2011<\/strong><\/p>\n\n\n\n

Ribeiro D, Ellwanger K*, Glagow D<\/strong>*, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C, Arenas E. Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis.<\/u><\/a> PLoS One<\/strong>. 2011 Feb 11;6(2):e15786. doi.org\/10.1371\/journal.pone.0015786<\/a>. PMID: 21347250<\/p>\n\n\n\n

2009<\/strong><\/p>\n\n\n\n

Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D<\/strong>, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Br\u00fcstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A. The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.<\/a> Cell Stem Cell<\/strong>. 2009 Aug 7;5(2):178-90. doi.org\/10.1016\/j.stem.2009.05.004<\/a>. PMID: 19664992<\/p>\n","protected":false},"excerpt":{"rendered":"

2026 Seib DR*, Liu MQ*, Tobiansky DJ, Floresco SB&, Soma KK&. A Novel Operant Conditioning Task to Assess Motivation to Exercise in Rats. *, co-author,\u00a0&\u00a0co-PI. BioRXiv 2026 July https:\/\/doi.org\/10.64898\/2026.07.07.7370 Ward MD, Snyder JS, Seib DR. Chemogenetic inhibition of developmentally-born hippocampal neurons but not loss of adult neurogenesis impairs spatial working […]<\/p>\n","protected":false},"author":351,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"_links":{"self":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages\/11"}],"collection":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/users\/351"}],"replies":[{"embeddable":true,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":7,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":230,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages\/11\/revisions\/230"}],"wp:attachment":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/media?parent=11"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/tags?post=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}