{"id":11,"date":"2024-05-06T12:09:36","date_gmt":"2024-05-06T15:09:36","guid":{"rendered":"https:\/\/projects.upei.ca\/seiblab\/?page_id=11"},"modified":"2026-06-24T16:01:26","modified_gmt":"2026-06-24T19:01:26","slug":"publications","status":"publish","type":"page","link":"https:\/\/projects.upei.ca\/seiblab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

2026<\/strong><\/p>\n\n\n\n

Ward MD, Snyder JS, Seib DR<\/strong>. Chemogenetic inhibition of developmentally-born hippocampal neurons but not loss of adult neurogenesis impairs spatial working memory in the rat. Behavioural Brain Research<\/strong> 2026 May 28:506:116151. https:\/\/doi.org\/10.1016\/j.bbr.2026.116151<\/a> PMID:\u00a041806956<\/p>\n\n\n\n

Jung MM, Idrissi M, Hoang Y, Huan T, Seib DR<\/strong>, Soma K. Maternal sucrose intake during pregnancy alone disrupts testosterone and allopregnanolone levels in the fetal brain of rats<\/a>. The Journal of Nutrition<\/strong> 2026 Feb;156(2):101267. https:\/\/doi.org\/10.1016\/j.tjnut.2025.101267<\/a> PMID:\u00a041386554<\/p>\n\n\n\n

2025<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Jung MM, Soma KK.\u00a0Maternal sucrose consumption alters steroid levels in the mother, placenta and fetus<\/a>.\u00a0Journal of Endocrinology<\/strong> 2025 Feb 24;265(1):e240238. https:\/\/doi.org\/10.1530\/JOE-24-0238<\/a> PMID:\u00a039873388<\/p>\n\n\n\n

2023<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Tobiansky DJ, Meitzen J, Floresco SB, Soma KK.\u00a0Neurosteroids and the mesocorticolimbic system<\/a>.\u00a0Neuroscience and Biobehavioral Reviews\u00a0<\/strong>2023 153, 105356.\u00a0https:\/\/doi.org\/10.1016\/j.neubiorev.2023.105356<\/a>.\u00a0PMID:\u00a037567491<\/p>\n\n\n\n

Price HR, Jalabert C,\u00a0Seib DR<\/strong>, Ma C, Lai\u00a0D, Soma KK, Collier AC.\u00a0Measurement of Steroids in the Placenta, Maternal Serum, and Fetal Serum in Humans, Rats, and Mice: A Technical Note<\/a>.\u00a0Separations<\/strong>\u00a02023\u00a010<\/em>(4), 221;\u00a0https:\/\/doi.org\/10.3390\/separations10040221<\/a>.\u00a0<\/p>\n\n\n\n

Ash AM, Regele-Blasco E,\u00a0Seib DR<\/strong>, Chahley E, Skelton PD, Luikart BW, Snyder JS.\u00a0Adult-born neurons inhibit developmentally-born neurons during spatial learning<\/a>.\u00a0Neurobiol. Learn. Mem.<\/strong>\u00a02023, 198, 107710.\u00a0doi.org\/10.1016\/j.nlm.2022.107710<\/a>.\u00a0PMID:\u00a036572174<\/p>\n\n\n\n

2022<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Princz-Lebel O, Chahley ER, Floresco SB, Snyder JS.\u00a0Hippocampal neurogenesis promotes effortful responding but does not regulate effort-based choice<\/a>.\u00a0Hippocampus<\/strong>\u00a02022 Sep 30.\u00a0 doi.org\/10.1002\/hipo.23472<\/a>. PMID:\u00a036177887<\/p>\n\n\n\n

O’Leary TP, Askari B, Lee B, Darby K, Knudson C, Ash AM,\u00a0Seib DR<\/strong>, Espinueva D, Snyder JS.\u00a0Inhibiting adult neurogenesis differentially affects spatial learning in females and males<\/a>.\u00a0eNeuro<\/strong>\u00a02022 May 12;9(3): ENEURO.0054-22.2022.\u00a0doi.org\/10.1523\/ENEURO.0054-22.2022<\/a>.\u00a0PMID: 35473765<\/p>\n\n\n\n

Tomm RJ*,\u00a0Seib DR*<\/strong>, Kachkovski GV, Schweitzer HR, Tobiansky DJ, Floresco SB&<\/sup>, Soma KK&<\/sup>.\u00a0Androgen synthesis inhibition increaes behavioural flexibility and tyrosine hydroxylase in gonadectomized male rats<\/a>. *, equal contribution,\u00a0&<\/sup>\u00a0co-PI.\u00a0J Neuroendocrinol\u00a0<\/strong>2022 Jun;34(6):e13128.\u00a0doi.org\/10.1111\/jne.13128<\/a>. PMID: 35583989<\/p>\n\n\n\n

2021<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Espinueva DF, Princz-Lebel O, Chahley E, Stevenson J, O’Leary TP, Floresco SB, Snyder JS.\u00a0Hippocampal neurogenesis promotes preference for future rewards<\/a>.<\/a>\u00a0Mol Psychiatry<\/strong>.\u00a02021 Nov;26(11):6317-6335.\u00a0doi: 10.1038\/s41380-021-01165-3. PMID: 34021262<\/p>\n\n\n\n

Comment by Thuret S: Faculty Opinions Recommendation<\/a><\/strong> of [Seib DR et al., Mol Psychiatry 2021]. In Faculty Opinions, 16 Jun 2021; 10.3410\/f.740158880.793585885<\/em><\/p>\n\n\n\n

2020<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Espinueva DF, Floresco SB, Snyder JS.\u00a0A role for neurogenesis in probabilistic reward learning.<\/a>\u00a0Behav Neurosci<\/strong>.\u00a02020 Aug;134(4):283-295.\u00a0doi.org\/10.1037\/bne0000370<\/a>.\u00a0Epub 2020 May 7. PMID: 32378907<\/p>\n\n\n\n

Cole JD, Espinueva DF,\u00a0Seib DR<\/strong>, Ash AM, Cooke MB, Cahill SP, O’Leary TP, Kwan SS, Snyder JS.\u00a0Adult-Born Hippocampal Neurons Undergo Extended Development and Are Morphologically Distinct from Neonatally-Born Neurons.<\/a>\u00a0J Neurosci<\/strong>.\u00a02020 Jul 22;40(30):5740-5756.\u00a0doi.org\/10.1523\/JNEUROSCI.1665-19.2020<\/a>.\u00a0Epub 2020 Jun 22.\u00a0PMID: 32571837<\/p>\n\n\n\n

Covered in Nature Research Highlights<\/strong><\/a>: Neurons that bloom in adulthood show off fancy patterns. 22 Jun 2020.<\/em><\/p>\n\n\n\n

2019<\/strong><\/p>\n\n\n\n

Yu RQ, Cooke M,\u00a0Seib DR<\/strong>, Zhao J, Snyder JS.\u00a0Adult neurogenesis promotes efficient, nonspecific search strategies in a spatial alternation water maze task.<\/a>\u00a0Behav Brain Res<\/strong>.\u00a02019 Dec 30;376:112151.\u00a0doi.org\/10.1016\/j.bbr.2019.112151<\/a>.\u00a0Epub 2019 Aug 22.\u00a0PMID: 31445978<\/p>\n\n\n\n

Cahill SP, Martinovic A, Cole JD,\u00a0Seib DR<\/strong>, Snyder JS.\u00a0A combination of running and memantine increases neurogenesis and reduces activation of developmentally-born dentate granule neurons in rats.<\/a>\u00a0Behav Brain Res<\/strong>.\u00a02019 Oct 17;372:112005.\u00a0doi.org\/10.1016\/j.bbr.2019.112005<\/a>.\u00a0Epub 2019 Jun 2.\u00a0PMID: 31167109<\/p>\n\n\n\n

2018<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Chahley E, Princz-Lebel O, Snyder JS.\u00a0Intact memory for local and distal cues in male and female rats that lack adult neurogenesis.<\/a>\u00a0PLoS One<\/strong>.\u00a02018;13(5):e0197869.\u00a0doi.org\/10.1371\/journal.pone.0197869<\/a>.\u00a0eCollection 2018.\u00a0PMID: 29787617<\/p>\n\n\n\n

2016<\/strong><\/p>\n\n\n\n

Snyder JS, Grigereit L, Russo A,\u00a0Seib DR<\/strong>, Brewer M, Pickel J, Cameron HA.\u00a0A Transgenic Rat for Specifically Inhibiting Adult Neurogenesis.<\/a>\u00a0eNeuro<\/strong>.\u00a02016 May-Jun;3(3).\u00a0doi.org\/10.1523\/ENEURO.0064-16.2016<\/a>.\u00a0eCollection 2016 May-Jun.\u00a0PMID: 27257630<\/p>\n\n\n\n

2015<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Martin-Villalba A.\u00a0Neurogenesis in the Normal Ageing Hippocampus: A Mini-Review.<\/a>\u00a0Gerontology<\/strong>.\u00a02015;61(4):327-35.\u00a0doi.org\/10.1159\/000368575<\/a>.\u00a0Epub 2014 Nov 29.\u00a0Review. PMID: 25471300<\/p>\n\n\n\n

2013<\/strong><\/p>\n\n\n\n

Seib DR<\/strong>, Corsini NS, Ellwanger K, Plaas C, Mateos A, Pitzer C, Niehrs C, Celikel T, Martin-Villalba A.\u00a0Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline.<\/a>\u00a0Cell Stem Cell<\/strong>.\u00a02013 Feb 7;12(2):204-14.\u00a0doi.org\/10.1016\/j.stem.2012.11.010<\/a>.\u00a0PMID: 23395445.<\/p>\n\n\n\n

Comment by Wu MV and Hen R. The young and the restless: regulation of adult neurogenesis by Wnt signaling.\u00a0Cell Stem Cell<\/a><\/strong>. 2013 Feb 7;12(2):139-40. doi.org\/10.1016\/j.stem.2013.01.013<\/a>.<\/em> PMID: 23395437<\/p>\n\n\n\n

Covered in National Geographic<\/a> <\/strong>by Virginia Hughes: Opening the Black Box of Neurogenesis. 7 Feb 2013.<\/em><\/p>\n\n\n\n

Seib DR<\/strong> and Martin-Villalba A (2013). In vivo<\/em><\/a> Neurogenesis<\/a>. Bio-protocol <\/strong>3(15): e841. http:\/\/doi.org\/10.21769\/BioProtoc.841<\/a>.<\/p>\n\n\n\n

Seib DR<\/strong> and Martin-Villalba A (2013). Neuronal Morphology Analysis<\/a>. Bio-protocol<\/strong> 3(15): e842. http:\/\/doi.org\/10.21769\/BioProtoc.842<\/a>.<\/p>\n\n\n\n

2011<\/strong><\/p>\n\n\n\n

Ribeiro D, Ellwanger K*,\u00a0Glagow D<\/strong>*, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C, Arenas E.\u00a0Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis.<\/u><\/a>\u00a0PLoS One<\/strong>.\u00a02011 Feb 11;6(2):e15786.\u00a0doi.org\/10.1371\/journal.pone.0015786<\/a>.\u00a0PMID: 21347250<\/p>\n\n\n\n

2009<\/strong><\/p>\n\n\n\n

Corsini NS, Sancho-Martinez I, Laudenklos S,\u00a0Glagow D<\/strong>, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Br\u00fcstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A.\u00a0The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair.<\/a>\u00a0Cell Stem Cell<\/strong>.\u00a02009 Aug 7;5(2):178-90.\u00a0doi.org\/10.1016\/j.stem.2009.05.004<\/a>. PMID: 19664992<\/p>\n","protected":false},"excerpt":{"rendered":"

2026 Ward MD, Snyder JS, Seib DR. Chemogenetic inhibition of developmentally-born hippocampal neurons but not loss of adult neurogenesis impairs spatial working memory in the rat. Behavioural Brain Research 2026 May 28:506:116151. https:\/\/doi.org\/10.1016\/j.bbr.2026.116151 PMID:\u00a041806956 Jung MM, Idrissi M, Hoang Y, Huan T, Seib DR, Soma K. Maternal sucrose intake during […]<\/p>\n","protected":false},"author":351,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"_links":{"self":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages\/11"}],"collection":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/users\/351"}],"replies":[{"embeddable":true,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":7,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":214,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/pages\/11\/revisions\/214"}],"wp:attachment":[{"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/media?parent=11"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/projects.upei.ca\/seiblab\/wp-json\/wp\/v2\/tags?post=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}