2026

Ward MD, Snyder JS, Seib DR. Chemogenetic inhibition of developmentally-born hippocampal neurons but not loss of adult neurogenesis impairs spatial working memory in the rat. Behavioural Brain Research 2026 May 28:506:116151. https://doi.org/10.1016/j.bbr.2026.116151 PMID: 41806956

Jung MM, Idrissi M, Hoang Y, Huan T, Seib DR, Soma K. Maternal sucrose intake during pregnancy alone disrupts testosterone and allopregnanolone levels in the fetal brain of rats. The Journal of Nutrition 2026 Feb;156(2):101267. https://doi.org/10.1016/j.tjnut.2025.101267 PMID: 41386554

2025

Seib DR, Jung MM, Soma KK. Maternal sucrose consumption alters steroid levels in the mother, placenta and fetusJournal of Endocrinology 2025 Feb 24;265(1):e240238. https://doi.org/10.1530/JOE-24-0238 PMID: 39873388

2023

Seib DR, Tobiansky DJ, Meitzen J, Floresco SB, Soma KK. Neurosteroids and the mesocorticolimbic systemNeuroscience and Biobehavioral Reviews 2023 153, 105356. https://doi.org/10.1016/j.neubiorev.2023.105356. PMID: 37567491

Price HR, Jalabert C, Seib DR, Ma C, Lai D, Soma KK, Collier AC. Measurement of Steroids in the Placenta, Maternal Serum, and Fetal Serum in Humans, Rats, and Mice: A Technical NoteSeparations 2023 10(4), 221; https://doi.org/10.3390/separations10040221

Ash AM, Regele-Blasco E, Seib DR, Chahley E, Skelton PD, Luikart BW, Snyder JS. Adult-born neurons inhibit developmentally-born neurons during spatial learningNeurobiol. Learn. Mem. 2023, 198, 107710. doi.org/10.1016/j.nlm.2022.107710. PMID: 36572174

2022

Seib DR, Princz-Lebel O, Chahley ER, Floresco SB, Snyder JS. Hippocampal neurogenesis promotes effortful responding but does not regulate effort-based choiceHippocampus 2022 Sep 30.  doi.org/10.1002/hipo.23472. PMID: 36177887

O’Leary TP, Askari B, Lee B, Darby K, Knudson C, Ash AM, Seib DR, Espinueva D, Snyder JS. Inhibiting adult neurogenesis differentially affects spatial learning in females and maleseNeuro 2022 May 12;9(3): ENEURO.0054-22.2022. doi.org/10.1523/ENEURO.0054-22.2022. PMID: 35473765

Tomm RJ*, Seib DR*, Kachkovski GV, Schweitzer HR, Tobiansky DJ, Floresco SB&, Soma KK&Androgen synthesis inhibition increaes behavioural flexibility and tyrosine hydroxylase in gonadectomized male rats. *, equal contribution, & co-PI. J Neuroendocrinol 2022 Jun;34(6):e13128. doi.org/10.1111/jne.13128. PMID: 35583989

2021

Seib DR, Espinueva DF, Princz-Lebel O, Chahley E, Stevenson J, O’Leary TP, Floresco SB, Snyder JS. Hippocampal neurogenesis promotes preference for future rewards. Mol Psychiatry. 2021 Nov;26(11):6317-6335. doi: 10.1038/s41380-021-01165-3. PMID: 34021262

Comment by Thuret S: Faculty Opinions Recommendation of [Seib DR et al., Mol Psychiatry 2021]. In Faculty Opinions, 16 Jun 2021; 10.3410/f.740158880.793585885

2020

Seib DR, Espinueva DF, Floresco SB, Snyder JS. A role for neurogenesis in probabilistic reward learning. Behav Neurosci. 2020 Aug;134(4):283-295. doi.org/10.1037/bne0000370. Epub 2020 May 7. PMID: 32378907

Cole JD, Espinueva DF, Seib DR, Ash AM, Cooke MB, Cahill SP, O’Leary TP, Kwan SS, Snyder JS. Adult-Born Hippocampal Neurons Undergo Extended Development and Are Morphologically Distinct from Neonatally-Born Neurons. J Neurosci. 2020 Jul 22;40(30):5740-5756. doi.org/10.1523/JNEUROSCI.1665-19.2020. Epub 2020 Jun 22. PMID: 32571837

Covered in Nature Research Highlights: Neurons that bloom in adulthood show off fancy patterns. 22 Jun 2020.

2019

Yu RQ, Cooke M, Seib DR, Zhao J, Snyder JS. Adult neurogenesis promotes efficient, nonspecific search strategies in a spatial alternation water maze task. Behav Brain Res. 2019 Dec 30;376:112151. doi.org/10.1016/j.bbr.2019.112151. Epub 2019 Aug 22. PMID: 31445978

Cahill SP, Martinovic A, Cole JD, Seib DR, Snyder JS. A combination of running and memantine increases neurogenesis and reduces activation of developmentally-born dentate granule neurons in rats. Behav Brain Res. 2019 Oct 17;372:112005. doi.org/10.1016/j.bbr.2019.112005. Epub 2019 Jun 2. PMID: 31167109

2018

Seib DR, Chahley E, Princz-Lebel O, Snyder JS. Intact memory for local and distal cues in male and female rats that lack adult neurogenesis. PLoS One. 2018;13(5):e0197869. doi.org/10.1371/journal.pone.0197869. eCollection 2018. PMID: 29787617

2016

Snyder JS, Grigereit L, Russo A, Seib DR, Brewer M, Pickel J, Cameron HA. A Transgenic Rat for Specifically Inhibiting Adult Neurogenesis. eNeuro. 2016 May-Jun;3(3). doi.org/10.1523/ENEURO.0064-16.2016. eCollection 2016 May-Jun. PMID: 27257630

2015

Seib DR, Martin-Villalba A. Neurogenesis in the Normal Ageing Hippocampus: A Mini-Review. Gerontology. 2015;61(4):327-35. doi.org/10.1159/000368575. Epub 2014 Nov 29. Review. PMID: 25471300

2013

Seib DR, Corsini NS, Ellwanger K, Plaas C, Mateos A, Pitzer C, Niehrs C, Celikel T, Martin-Villalba A. Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline. Cell Stem Cell. 2013 Feb 7;12(2):204-14. doi.org/10.1016/j.stem.2012.11.010. PMID: 23395445.

Comment by Wu MV and Hen R. The young and the restless: regulation of adult neurogenesis by Wnt signaling. Cell Stem Cell. 2013 Feb 7;12(2):139-40. doi.org/10.1016/j.stem.2013.01.013. PMID: 23395437

Covered in National Geographic by Virginia Hughes: Opening the Black Box of Neurogenesis. 7 Feb 2013.

Seib DR and Martin-Villalba A (2013). In vivo NeurogenesisBio-protocol 3(15): e841. http://doi.org/10.21769/BioProtoc.841.

Seib DR and Martin-Villalba A (2013). Neuronal Morphology AnalysisBio-protocol 3(15): e842. http://doi.org/10.21769/BioProtoc.842.

2011

Ribeiro D, Ellwanger K*, Glagow D*, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C, Arenas E. Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. PLoS One. 2011 Feb 11;6(2):e15786. doi.org/10.1371/journal.pone.0015786. PMID: 21347250

2009

Corsini NS, Sancho-Martinez I, Laudenklos S, Glagow D, Kumar S, Letellier E, Koch P, Teodorczyk M, Kleber S, Klussmann S, Wiestler B, Brüstle O, Mueller W, Gieffers C, Hill O, Thiemann M, Seedorf M, Gretz N, Sprengel R, Celikel T, Martin-Villalba A. The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair. Cell Stem Cell. 2009 Aug 7;5(2):178-90. doi.org/10.1016/j.stem.2009.05.004. PMID: 19664992